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Study identifies key factor in DNA damage associated with aging
In a recent study, Rochester scientists made two important contributions to DNA damage research. First, though scientists could previously point to an association between DNA damage and aging, the Rochester group has demonstrated a causal relationship between reduced DNA damage and extended lifespan. Second, the researchers have identified a cellular factor—an enzyme called topoisomerase 2, or Top2, implicated in DNA damage—that can be targeted to reduce that damage. The findings are published...
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| Categories: | Tags: Aging, Arts and Sciences, David Goldfarb, Department of Biology, DNA, research finding, replicative lifespan, aging, topoisomerase 2 poison, DNA damage, antagonistic pleiotropy | Comments: (0) | View Count: (744)