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Epigenetic clock analyses of cellular senescence and ageing
A confounding aspect of biological ageing is the nature and role of senescent cells. It is unclear whether the three major types of cellular senescence, namely replicative senescence, oncogene-induced senescence and DNA damage-induced senescence are descriptions of the same phenomenon instigated by different sources, or if each of these is distinct, and how they are associated with ageing.
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| Categories: | Tags: DNA methylation, ageing, senescence, DNA damage, radiation, Gerotarget | Comments: (0) | View Count: (1463)
Blood epigenetic age may predict cancer incidence and mortality
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are chronologically.
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| Categories: | Tags: epigenetic age, cancer risk, DNA methylation | Comments: (0) | View Count: (1415)